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Image Search Results
Journal: Frontiers in Oncology
Article Title: Transcriptome-Wide Map of N 6 -Methyladenosine Methylome Profiling in Human Bladder Cancer
doi: 10.3389/fonc.2021.717622
Figure Lengend Snippet: Prognostic value of the survival-associated gene signature in bladder cancer patients. (A) Validations of the m 6 A enrichments of 10 hypermethylated genes and 10 hypomethylated genes by m 6 A-immunoprecipitation (IP)-qPCR. (B) Validations of the mRNA expression levels of 10 upregulated genes and 10 downregulated genes by RT-qPCR. (C–H) The low expressions of METTL14 (C) , SMPD4 (E) , and SGK2 (F) in mRNA level correlate with worse overall survival in bladder cancer patients. The high expression of ALKBH5 (D) , LINC00482 (G) , and HIPK (H) expression levels showed a tendency to correlate with worse overall survival in bladder cancer patients. *p < 0.05, **p < 0.01.
Article Snippet:
Techniques: Immunoprecipitation, Expressing, Quantitative RT-PCR